High Titers of Hemagglutination Inhibition Antibodies against 2009 H1N1 Influenza Virus in Southern Iran
Authors
Abstract:
Background: Pandemic flu had at least two waves in Iran. Knowing how many of the general population were already exposed to this infection has a major impact on na-tional preventive measures. As of December 30, 2009, a total of 3672 confirmed cases of human infection with a novel Influenza A (2009 H1N1) virus had been reported in Iran with 140 deaths. Objective: In this study we aim to measure, as a pilot study, the seroprevalence of positive antibody titer (humoral immunity) against 2009 H1N1 virus in Iranian population in Shiraz, Southern Iran. Methods: Through cluster random sam-pling of families residing in Shiraz, 2553 subjects were selected and after a medical in-terview blood samples were taken and checked for polyclonal antibody against 2009 H1N1 antigen using hemagglutination inhibition assay. An antibody titer of more than 1:40 dilution was considered positive. Data were analyzed considering the demographic characteristics of the population and were compared among different age groups. Results: 1504 (58.91%) samples were tested positive for the presence of polyclonal an-tibody against 2009 H1N1 virus. The prevalence of positive titers were significantly higher in 60 to 64 years old group and significantly lower in 20 to 24 years old group (p
similar resources
high titers of hemagglutination inhibition antibodies against 2009 h1n1 influenza virus in southern iran
background: pandemic flu had at least two waves in iran. knowing how many of the general population were already exposed to this infection has a major impact on na-tional preventive measures. as of december 30, 2009, a total of 3672 confirmed cases of human infection with a novel influenza a (2009 h1n1) virus had been reported in iran with 140 deaths. objective: in this study we aim to measure,...
full textRate of decline of antibody titers to pandemic influenza A (H1N1-2009) by hemagglutination inhibition and virus microneutralization assays in a cohort of seroconverting adults in Singapore
BACKGROUND The rate of decline of antibody titers to influenza following infection can affect results of serological surveys, and may explain re-infection and recurrent epidemics by the same strain. METHODS We followed up a cohort who seroconverted on hemagglutination inhibition (HI) antibody titers (≥ 4-fold increase) to pandemic influenza A(H1N1)pdm09 during a seroincidence study in 2009. A...
full textSerological prevalence of avian H9N2 influenza virus in dogs by hemagglutination inhibition assay in Kerman, southeast of Iran
Influenza is a highly contagious zoonotic disease in the world. Avian H9N2 influenza virus is a significant pandemic pathogen widely distributed throughout the world. Pet ownership has been documented as a risk factor for infection transmission to human. Considering major public health concern, the prevalence of antibodies against avian H9N2 influenza virus was evaluated in 170 serum samples of...
full textPrevalence of Oseltamivir-Resistant 2009 H1N1 Influenza Virus among Patients with Pandemic 2009 H1N1 Influenza infection in NRITLD, Tehran, Iran
BACKGROUND Oseltamivir-resistant cases were reported during the 2009 pandemic influenza outbreak and therefore, widespread emergence of oseltamivir-resistant 2009 H1N1 virus is imaginable. Underlying medical conditions like immunosuppression increase the chance of oseltamivir resistance. MATERIALS AND METHODS In a retrospective cross-sectional study, respiratory tract specimens of confirmed c...
full textCross-reacting antibodies against the pandemic (H1N1) 2009 influenza virus in older Australians.
OBJECTIVE To assess background pre-pandemic cross-reacting antibodies to the pandemic (H1N1) 2009 virus in older populations in Australia. DESIGN, SETTING AND PARTICIPANTS Data were opportunistically generated from three cross-sectional pre-pandemic studies involving people aged 60 years or older: a 3-year (2006-2008) study of influenza outbreaks in aged care facilities (ACFs) in Sydney; an i...
full textMy Resources
Journal title
volume 7 issue 1
pages 39- 48
publication date 2010-03-01
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023